Suppression of Studies
Posted: Tue Jun 03, 2014 1:27 pm
I read an article on Psychology Today titled No, It’s Not the Neurotransmitters, which says, among other things:
A) Pharmaceutical companies "suppress" scientific studies, or significantly affect which studies are published...
B) The available evidence does not demonstrate the effectiveness of antidepressant medications...
C) Chemical imbalance is probably not the root cause of most cases of depression...
D) People with depression will generally be more likely to feel less depressed if they undergo forms of treatment other than taking antidepressants, (e.g. psychotherapy)...
E) Taking antidepressants ultimately makes depression worse for most people who take them, or has other negative side effects which end up making the patients feel worse than they otherwise would have.
(Please note that I do not intend to imply personal agreement with any of these claims, I simply wish to express them to solicit feedback on what others think their probable truth values are.)
I thought perhaps folks here had already been confronted with similar claims in the past and may have already done some fact checking. I'm curious if people here agree or disagree that:The pharmaceutical industry has been exposed having been engaged in study suppression, falsification, strategic marketing, and financial incentives. Sales of antidepressants in 2011 was 11 billion dollars. Ben Goldacre is his illuminating Ted lecture, “What doctors don't know about the drugs they prescribe” addressed the issue of study suppression. A fifteen year review of antidepressant studies showed that 50% of the 76 studies were positive and 50% were negative. All of the positive studies were published and all but three of the negative studies were suppressed and not published. In 2004 approximately half of all studies that weren’t already suppressed by the pharmaceutical industry concluded that antidepressants are not significantly more effective than placebo alone. And two thirds of studies for children given antidepressants show the same.
A) Pharmaceutical companies "suppress" scientific studies, or significantly affect which studies are published...
B) The available evidence does not demonstrate the effectiveness of antidepressant medications...
C) Chemical imbalance is probably not the root cause of most cases of depression...
D) People with depression will generally be more likely to feel less depressed if they undergo forms of treatment other than taking antidepressants, (e.g. psychotherapy)...
E) Taking antidepressants ultimately makes depression worse for most people who take them, or has other negative side effects which end up making the patients feel worse than they otherwise would have.
(Please note that I do not intend to imply personal agreement with any of these claims, I simply wish to express them to solicit feedback on what others think their probable truth values are.)